If you need to establish an online business in the UAE’s mainland, you have to apply through the Department of Economic Development (DED) in the respective emirate. All eTrade licences require the approval of Telecommunications and Digital Government Regulatory Authority also, which is in charge of regulating the eCommerce framework and transactions in the UAE. Find out the service to apply for non- objection certificate to practice eTrade. 

Read about 

• Electronic Transactions and Trust Services Law ( Available in Arabic only)
• eCommerce platforms-Ministry of Economy

• UAE e-commerce market forecast to reach $9.2 billion by 2026.